What does it publish?

Original research, reviews, clinical case reports and commentary across all subspecialties of internal medicine.

Does it cost anything?

No. No submission fee, no article processing charge and no publication fee, at any stage.

How is peer review done?

An editor screens each manuscript for scope, ethics, reporting standards and similarity; it then goes to double-anonymous peer review.

Yes. Every article is free to read on publication under a CC BY 4.0 licence, with a Crossref DOI.

Listed in the Directory of Open Access Journals (DOAJ). ISSN 3065-968X.

Read the author guidelines (https://asidejournals.com/index.php/internal-medicine/about/submissions), then submit online (https://asidejournals.com/index.php/internal-medicine/submission).

ASIDE Internal Medicine | No-APC Open-Access Journal

Articles

Vol. 2 No. 6 (2026): Volume 2 Issue 6 Online First / Ahead of Print

Long-Term Trends in Sepsis Mortality Among Older U.S. Adults with Chronic Kidney Disease, 1999–2023

Umar Aziz, Roshni Riaz Memon, Muhammad Mussawir Khuhro, Huda Ahmed, Sarah Azhar, Hamama Waseem, Maryam Waqar, Muhammad Waaiz, Mominah Majid, Raveen Mujeeb

1-10

Periprosthetic Joint Infection in Egypt: A Narrative Review of the Current Landscape and Knowledge Gaps

Asem Mohsen, Mostafa Alfishawy

11-19

Short-Term Changes in Hematologic Inflammatory Indices During Exenatide Therapy in Patients with Type 2 Diabetes Mellitus

Cigdem Cindoglu, Hüseyin Karaaslan, Nida Uyar, Ali Gökçe, Burcu Dikeç Gökçe, Mehmet Ali Eren

20-25

Psychological Burden in Behçet Disease: A Narrative Review Across Mucocutaneous, Articular, and Ocular Manifestations

Ahmed Ismael, Ahmed Mabrouk, Mahmoud Zeinhom Ramadan, Hussein Eldamery, Assem Amer, Mohamed Fouad M Ragab, Sherif Helal, Elsadek Helal E. Mahdi, Sherin A Ghaith, Mahmoud M Saber Abdelwahed, Mohammad M. Badran, Ashraf E.M. Ebaid

26-33

Fatal Septic Shock with Presumed Urinary Source in a Patient with Clinically Suspected, Previously Undiagnosed Von Hippel–Lindau Disease: A Case Report and Literature Review

Talha Khan, Hasnain Wajeeh Saqib, Syed Tahir Hussain, Ahmad Mustafa Butt, Muhammad Hassaan Javaid, Awais Hussain Kazim, Aqsa Ibrahim, Saif Ali Khan, Noor Ül-Izza, Abdullah Abbas

34-40

Community-Based Harm Reduction Programs for Opioid Use Disorder: A Narrative Systematic Review of Effectiveness, Implementation Barriers, and Policy Implications

Eloghosa Aisosaa Nosa-Ihaza, Ssembuusi Allan Francis

41-55

Vol. 2 No. 5 (2026): Volume 2 Issue 5 Online First / Ahead of Print

Low-Grade Inflammation and Oxidative Stress as Drivers of Obesity-Related Complications: A Narrative Review

Kazheen Majeed, Hazhmat Ali

1-10

HIV in Egypt: from Silent Emergence to Concentrated Epidemic - A Narrative Review of Past, Present, and Future

Asem Mohsen, Mostafa Alfishawy

11-23

Losartan Monotherapy vs Combination Regimens in IgA Nephropathy: A Systematic Review and Network Meta-analysis

Mohamed E. Haseeb, Hazem E. Mohammed, Anas Hussein Heiba, George Hanen, Nada Ali Omar Abd Elaziz, Mohamed Nasser

24-34

Efficacy and Safety of Isotretinoin Plus Desloratadine versus Isotretinoin Alone for Acne Vulgaris: Systematic Review and Meta-analysis

Ahmed S Mohamed, Mazen Kafienah, Meena Rabi, Paul Fabian, Ali Gebril Ali, Mohamed Ali Abdel Rahman, Ayla Amjad, Eslam Seddik

35-49

Biomarkers in Hemophilia: Diagnostic, Prognostic, and Treatment-Selection Utility: A Narrative Review of the Literature

Dalia Atef Abouda, Elsayed S. Moubarak, Fatma ElBadrawy, Malak A. Hassan, Mohamed Mohsen Helal, Abdallah M. Ibrahim, Hassan H. Eladl, Mohammad Mahadin, Mohamed Elsaid

50-60

Vol. 2 No. 4 (2026): Volume 2, Issue 4 Online First / Ahead of Print

Dexmedetomidine as an Adjuvant to Ropivacaine in Thoracic Paravertebral Block: A Systematic Review with Meta-analysis

Mohamed Wagdy, Abdelrahman Abdalla Mohamed, Abdalla Ahmed Mohamed, Ziad ElDosoky Farouk, Mahmoud Abd El-Nasser, Abdelrahman A. Ebaid, Abdelrhman Waleed Kotb, Mostafa AbdElmawla Mohamed

1-8

Posterior Reversible Encephalopathy Syndrome (PRES) Beyond Hypertension: Triggers, Pathophysiology, Management, and Outcomes

Mohamed Fawzi Hemida, Pranjal Kumar Singh, Alyaa Ahmed Ibrahim, Ahmed Harb, Sai Lokesh Moraboina, Geethanjali Prakash, Esraa M. Soliman, Arun Kumar Maloth, Huda Adnan, Ravi Virani, Sanchit Shailendra Chouksey

9-16

Multiple Myeloma and Chronic Kidney Disease–Related Mortality, 1999–2023: A Population-Based Time-Trend Analysis

Alyaa Ahmed Ibrahim, Mohamed Fawzi Hemida, Amro Ali, Raveen Mujeeb, Mohammad Rayyan Faisal, Mahmoud Tablawy, Krish Patel, Maryam Saghir, Eshal Saghir, Sara Hasanin, Ahmed Atef Mohamed, Safeya Fawzi, Arwa Khaled Dessouky, Ahmed Khairy, Asmaa Mohamed, Abdelrhman H. Mohamed, Abdullah Farahat Elbanna

17-25

Infective Endocarditis with Severe Aortic Regurgitation Complicated by Type A Aortic Dissection in a Tricuspid Aortic Valve: A Case Report

Zubair Ahmed, Farhan Ali, Muqadas Fatima, Falak Naz, Shaista Ali, Jawad Asad, Vinta

26-29

Demographic Factors of Colorectal Cancer (CRC) Patients with Paralytic Ileus Among Adults in the United States: A Retrospective Study for Mortality Trends

Waheed Qaisi, Mirna Hussein, Pakeezah Tabasum, Mohamed Wagdy, Nidal Mutawodeh, Abdallah Abdallah, Mohammed Mereb, Youssef Heikal

30-36

Artificial Intelligence in the Evaluation of Abnormal Liver Tests and MASLD: Emerging Applications in Risk Stratification and Clinical Decision Support

Ahmed Salman

37-45

Pulmonary Alveolar Microlithiasis-like Process in Pregnancy with Concurrent Pneumothorax: A Case Report

Ayrton Borg Axisa, Jessica Zammit, Christopher Zammit, Luca Conti

46-53

Vol. 2 No. 3 (2026): Volume 2, Issue 3

Improving Inpatient Care for Acute Chronic Obstructive Pulmonary Disease Exacerbations: A Quality Improvement Initiative

Khaqan Ahmed, Afaq Ahmad, Muhammad Saqib, Muhammad Iftikhar, Humna Shahid

1-10

A Pairwise and Network Meta-Analysis Comparing the Efficacy and Safety of Ribonucleic Acid Interference Therapeutics in the Management of Hypertension

Mohamed E. Haseeb, Zeyad Bady, Hazem E. Mohammed, George Hanen, Mohamed Nasser, Nada S. Jibril, Mohamed Khalafalla Darwish, Heba Aboeldahab

11-23

Disparities and Trends in Polycythemia Vera–Related Mortality in U.S. Adults Aged ≥45 Years from 1999 to 2023

Alyaa Ahmed Ibrahim, Mohamed Fawzi Hemida, MD, Mirna Hussein, Maryam Saghir, Mohammad Rayyan Faisal, FNU Kritika, Krish Patel, Amro Ali, MD, Eshal Saghir, Mahmoud Tablawy, Abdelrhman H. Mohamed, Amr Arafa, MD

24-32

Twenty-Five Years of Angina–Related Mortality in Elderly Adults Aged ≥ 65 Years: A Retrospective Cohort Study Using Real-World Data from the USA

Mohamed Fawzi Hemida, Alyaa Ahmed Ibrahim, Anika Goel, Mirna Hussein, Krish Patel, Muhammad Raza Sarfraz, Omar Y. Alkasabrah, MD, Maryam Saghir, Komal Karmani, Eshal Saghir, Zahin Shahriar, Safeya Fawzi, Ahmed Bahnasy, Muhammad Faizan Ali, Amro Ali, Ahmad M. Abdelkhalek, Raheel Ahmed, MBBS, MRCP, PhD

33-42

National-Level Outcomes of Diabetic Ketoacidosis with and without Coma: A Retrospective Analysis of 2.3 Million U.S. Hospitalizations

Mahmoud Nassar, Mohamed Hatem Ellabban, Mohamed R. Murad, Omar Nassar, Nuha ElSayed

43-54

Adjunctive Remotely Supervised tDCS in Multiple Sclerosis: A GRADE-Assessed Meta-Analysis of Sham-Controlled Trials on Cognitive, Fatigue, Mobility, and Quality-of-Life Outcomes

Omar Khaled Abdelsalam, Mousa Almasalma, Ali Nagy Shelbaya, Ahmed Raja Albishti, Mohamed H. Khalil, Hamza Khelifa, Ahmed Abdelsalam, Asmaa Zakria Alnajjar

55-64

Vol. 2 No. 2 (2026): Volume 2, Issue 2

Lifestyle Practices in Reducing Cardiovascular Diseases: A Prospective Cohort Study from Pakistan

Humna Shahid, Muhammad Saqib, Muhammad Iftikhar, Shehr I Yar Khan, Muhammad Ahsan, Hashir Ali Shah, Umama Amjad, Muhammad Nadeem Khan, Saiyad Ali, Dr. Hassan Mumtaz

1-5

Bridging the Gap between Evidence and Practice: Nationwide Retrospective Analysis of Lipid-Modifying Therapy Prescription Patterns in 5 Million Patients with Type 2 Diabetes Mellitus

Ahmed Hassan, Menna A. Keshk, Mohamed Reyad, Nourhan Ahmed, Omar Nassar, Aisha Siraj, Salem Badr, Sherif Eltawansy, Anoop Misra, Muhammed Amir Essibayi, Ahmed Y. Azzam, Mahmoud Nassar, Diaa Hakim

6-11

Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report With Vertigo, Dysmetria, And Impaired Tandem Gait

Ali Al Yasari, Mahdia Alhaidar, Mohamad Assker

12-16

Prolonged Immunosuppressive Therapy in Immune Complex-Membranoproliferative Glomerulonephritis: A Case Report of Sustained Partial Remission Over Three Years

Kubra Kaynar, Yasin Dilek, Mert Köse, Sevdegül Aydın Mungan

16-20

Trends in Mortality from Leukemia and Ischemic Heart Disease: A 22-Year Analysis in the U.S. (1999-2020)

Mohamed Fawzi Hemida, Ayesha Khan, Alyaa Ahmed Ibrahim, Anika Goel, Krish Patel, Zahin Shahriar, Ahmed W. Hageen, Mustafa Alsaadi, Saif Ur Rahman, Amr Arafa, Zeyad Kholeif, Ahmed Bahnasy

21-30

Vol. 2 No. 1 (2026): Volume 2, Issue 1 (2026)

A Comprehensive Review of Fluid Resuscitation Techniques in Sepsis in Patients with Heart Failure

Mallikarjuna S. oruganti, Sameena Tabassum, Anushree V. Murthy, Navya.Miriyala, Nitasha, Sunil Timilsina

1-7

Epidemiological Assessment of Risk Factors for Inguinal Hernia Among Male Patients in Iraq: A Case-Control Study

Ali Abdul Jabbar Mahdi, Taqi Mohammed Jwad Taher, Rami Bahaa Saadi

8-12

Concurrent Diabetic Ketoacidosis and Acute Coronary Syndrome: A Systematic Review of Case Reports

Ahmed Elbataa, Ahmed Farid Gadelmawla, Laila Mohamed Akr, Mohamed Yasser Elnaggar, Mohamed Mahmoud, Alaa Abdrabou Abouelmagd, Omar Nassar, Ahmed Hassan

13-22

Esophageal Stenting and Endoscopic Vacuum Therapy for Esophageal Defects: A Systematic Review and Meta-Analysis

Muhammad Saqib, Muhammad Iftikhar, Khaqan Ahmed, Humna Shahid, Shehr I Yar Khan, Muhammad Aamir Iqbal, Hassan Mumtaz

23-32

Migraine Headache in Patients with Allergic Rhinitis: A Systematic Review and Meta-Analysis of Observational Studies

Ahmed Talaia, Khaled Kettaneh, Ayoub Ait Lahcen, Abdeljalil El Hilali, Mohamed Magdi, Marwa Amayem, Mohamed Wagdy, Shrouk Mahmoud Elghazaly

33-40

Vol. 1 No. 4 (2025): Volume 1, Issue 4 (2025)

Human Readers versus AI-Based Systems in ASPECTS Scoring for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis with Region-Specific Guidance

Ahmed Y Azzam, Ibrahim Hadadi, Leen M. Al-Shahrani, Ummkulthum A. Shanqeeti, Noor A. Alqurqush, Mohammed A. Alsehli, Rudaynah S. Alali, Rahaf S. Tammar, Mahmoud M. Morsy, Muhammed Amir Essibayi

1-9

Mechanism of action of probiotics in wound and burn management.

Probiotics: A Promising Ally in Burn Treatment

Kholoud Al Jebawi, Jobran Toami, Adel Ayash, Razan Salha, Mira Al Shoufy, Jamil Nasrallah, Naseeb Danaf, Lea El Ghawi, Layal Msheik, Hiba Hamdar

10-17

Dual association of autoimmune encephalitis with anti-NMDAR and anti-GAD65 antibodies: A Case Report with Literature Review

Oumaima Rian, Wafa Ammouri, Latifa Oualili, Mouna Maamer, Tarek Dendane, Hicham Harmouche, Khalid Abidi

18-22

Bridging the Gap: Addressing Language Barriers to Advance Equity in Internal Medicine

Jayashree Ravikumar, Divya Ravikumar

23-30

Clinical Efficacy and Safety of Fluvoxamine in COVID-19 Patients: An Umbrella Review of Systematic Reviews and Meta-Analyses

Omar Irfan, Muhammad Jansher, Wania Moeen, Muhammad Sohaib Khan, Muhammad Bin Hammad, Rubaid Dhillon, Nabira Khan, Abia Abdullah, Mohammad Aadil Qamar, Ayesha Rashid, Javaid Ahmed Khan, Ali Bin Sarwar Zubairi

31-41

Vol. 1 No. 3 (2025): Volume 1, Issue 3 (2025)

Antibiotic Knowledge, Perception, and Practice of Intern Doctors in Turkey: A Survey Study

AHMET DOĞAN, Azra SÖNMEZ, Beyza DİŞLİ, Hasan Şamil ÇELİK, Chingiz RUSTAMLİ, Ecem Berra NAZLIOĞLU, Zuhat ABDULKERİMOĞLU, Mustafa Talha ALTUNBAŞ, Rumeysa ÖZER

1-6

Efficacy and Safety of Optic Nerve Sheath Fenestration for Idiopathic Intracranial Hypertension: A Subgroup-Focused Systematic Review and Meta-Analysis

Feras Almasoud, Abduljabbar Alabduljabbar, Abdulaziz Alotaibi, Abdulbari Hanash, Yazeed Bader Alaql, Abdulwahab Alshehri, Yousef Almohammadi, Mohammad Alenazi, Abdulmajeed Alharbi, Muhammed Amir Essibayi, David J Altschul, Ahmed Y. Azzam

7-14

Efficacy and Safety of Penehyclidine Hydrochloride in Postoperative Nausea and Vomiting Prevention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Ahmed Magdy Hassan, Eithar Alqady, Mohamed Wagdy, Ahmed T. Shalby, Mahmoud Abdelkader, Karim Osamy, Alaa Anter, Ihab Tarik, Manar Samy, Sherif Eltawansy, Ahmed Hassan

15-21

Challenges and Infectious Complications in Living Donor Liver Transplantation in Egypt: A Comprehensive Review

Ahmed Mohamed Ali Aref, Ahmed H. Abdelwahed, Abdelrahman Nassar, Mohamed Elshennawy, Maryam Massoud, Nada Madkour, Esraa Awad, Fatma Aljalawy, Mohamed Akram Abdelwahab Hassan Khalil, Mohammed Y. Youssef, Omar Nassar, Mostafa Alfishawy

22-27

Acute Myeloid Leukemia Presenting as Bilateral Proptosis: A Case Report with Literature Review

Ahmed Mostafa Youssef, Mohamad Monif Assker, Farah Alkhaleefa , Mahasin Shaheen

28-33

Vol. 1 No. 2 (2025): Volume 1, Issue 2 (2025)

Geographic Distribution of Diabetes Mellitus Cases in the United States

Epidemiological Patterns of Diabetes Mellitus in The United States of America: An Observational Multicenter Analysis From 1990 to 2024

Ahmed Y. Azzam, Luis Medina Mora, Mahmoud M. Morsy, Muhammed Amir Essibayi, David J. Altschul, Mahmoud Nassar

1-7

Prevalence of Metabolic-Associated Steatotic Liver Disease in Patients with Type 2 Diabetes with and without HIV: Retrospective Multicenter Study

Hazem Abosheaishaa, Omar Nassar, Mostafa Alfishawy, Anthony Martinez

8-12

Investigating the Impact of Primary Education on Birth Control Practices in Bangladesh: A Primary Study

Md Rakibul Hasan, Kanij Fatema Rabu, Moryom Akter Muna, Sajid Hassan, Saifur Rahman

13-19

Impact of Serum Adiponectin Level on Insulin and hs-CRP in Patients with Type 2 Diabetes: A Case-Control Study

Hind F Jawad, Shatha H Ali, Mustafa S Jawad

20-23

TriNetX Strengths, Limitations, and Bias Considerations in Clinical Research

TriNetX and Real-World Evidence: A Critical Review of Its Strengths, Limitations, and Bias Considerations in Clinical Research

Mahmoud Nassar, Hazem Abosheaishaa, Khaled Elfert, Azizullah Beran, Abdellatif Ismail, Mouhand Mohamed, Anoop Misra, Muhammed Amir Essibayi, David J. Altschul, Ahmed Y. Azzam

24-33

Vol. 1 No. 1 (2025): Volume 1, Issue 1 (2025)

The Impact of Idiopathic Intracranial Hypertension on Cardiovascular Disease Risk Among UK Women: An Obesity-Adjusted Analysis

Ahmed Y. Azzam, Mahmoud M. Morsy, Mohamed Hatem Ellabban, Ahmed M. Morsy, Adham Adel Zahran, Mahmoud Nassar, Omar S. Elsayed, Adam Elswedy, Osman Elamin, Ahmed Saad Al Zomia, Hana J. Abukhadijah, Hammam A. Alotaibi, Oday Atallah, Mohammed A. Azab, Muhammed Amir Essibayi, Adam A. Dmytriw, Mohamed D. Morsy, David J. Altschul

1-10

Figure 1: Mechanisms of Action of Metformin in IIH

Safety and Efficacy of Metformin for Idiopathic Intracranial Hypertension: A U.S.-Based Real-World Data Retrospective Multicenter Cohort Study

Ahmed Y. Azzam, Mahmoud Nassar, Ahmed Saad Al Zomia, Adam Elswedy, Mahmoud M. Morsy, Adham A. Mohamed, Osman Elamin, Omar S. Elsayed, Mohammed A. Azab, Muhammed Amir Essibayi, Jin Wu, Adam A. Dmytriw, David J. Altschul

11-17

Investigating Racial Disparities in Insulin Pump Use Among People with Type 1 Diabetes Across the United States: A Retrospective Multicenter Study

Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Iqra Patoli, Angad Gill, Erlin J. Marte

18-23

figure 1: Cox-Hazard Survival Curve By Anatomical Site

Real-World Epidemiological Analysis of Gastrointestinal Neuroendocrine Carcinomas: A TriNetX-Based Study

Bahaaeldin Baraka, Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Eyad Ibrahim, Jin Wu, Ahmad Ghorab

24-30

Epidemiological Patterns, Treatment Response, and Metabolic Correlations of Idiopathic Intracranial Hypertension: A United States-Based Study From 1990 to 2024

Ahmed Y. Azzam, Mahmoud Nassar, Mahmoud M. Morsy, Adham A. Mohamed, Jin Wu, Muhammed Amir Essibayi, David J. Altschul

31-39

ASIDE Internal Medicine at a glance

What does it publish?: Original research, reviews, clinical case reports and commentary across all subspecialties of internal medicine.
Does it cost anything?: No. No submission fee, no article processing charge and no publication fee, at any stage.
How is peer review done?: An editor screens each manuscript for scope, ethics, reporting standards and similarity; it then goes to double-anonymous peer review.
Is it open access?: Yes. Every article is free to read on publication under a CC BY 4.0 licence, with a Crossref DOI.
Where is it indexed?: Listed in the Directory of Open Access Journals (DOAJ). ISSN 3065-968X.
How do I submit?: Read the author guidelines, then submit online. Questions? Our Help Center starts here.

About the Journal

ASIDE Internal Medicine is a peer-reviewed, open-access journal for clinicians and researchers in internal medicine and its subspecialties. There is no fee to submit and no fee to publish.

The journal is published and owned by the American Society for Inclusion, Diversity, and Equity in Healthcare (ASIDE), 16192 Coastal Highway, Lewes, Delaware 19958, USA.

What we publish

Original research, case reports, systematic and narrative reviews, brief communications, clinical images and editorials across general internal medicine and its subspecialties. We welcome work on health equity, the social determinants of health and access to care for under-served populations.

Why authors choose ASIDE Internal Medicine

No article processing charge: submission, peer review and publication are free for every author
Double-anonymous peer review
Immediate open access under CC BY 4.0
A Crossref DOI for every article
Listed in the Directory of Open Access Journals (DOAJ)

Read the call for submissions or see the author guidelines.

ISSN (Print) 3065-9671 · ISSN (Online) 3065-968X

Publication frequency: continuous publication, with articles collected into issues (Volume 1, 2025: four issues; Volume 2, 2026: six issues). Accepted articles may be published online before assignment to a regular issue; the online publication date is the official first publication date. When an article is later assigned to an issue, its record is updated with the final volume, issue and article identifier. The DOI does not change.