Keywords
Mycophenolic acid
Remission induction
Categories
Date
- Submitted: Jun 23, 2025
- Published: Sep 4, 2025
How to Cite
Abstract
The prevalence of membranoproliferative glomerulonephritis (MPGN) is very low among primary glomerulonephritis. Once MPGN is diagnosed, it is essential to classify the type of MPGN [immune complex (IC), complement-mediated, and without complement or IC deposition]. In cases of IC-MPGN, secondary causes should be thoroughly investigated. However, there are no randomised controlled prospective trials for the optimal treatment regime for primary IC-MPGN. Here, we present a report of primary IC-MPGN that achieved partial remission after 3 years of mycophenolate mofetil treatment, even though significant fibrosis was present in the kidney biopsy. This report may support consideration of prolonged immunosuppression in selected cases with primary IC-MPGN.
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Copyright (c) 2025 Kubra Kaynar, Yasin Dilek, Mert Köse, Sevdegül Aydın Mungan