Antibiotic Knowledge, Perception, and Practice of Intern Doctors in Turkey:  A Survey Study
ASIDE IM issue 3
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Keywords

Antibiotic knowledge
Antibiotic resistance
Antibiotic stewardship
Intern doctors
Survey study
Turkey

Categories

How to Cite

1.
DOĞAN A, SÖNMEZ A, DİŞLİ B, et al. Antibiotic Knowledge, Perception, and Practice of Intern Doctors in Turkey:  A Survey Study. ASIDE Int Med. 2025;1(3):1-6. doi:10.71079/ASIDE.IM.1442541

Abstract

Background: This study aimed to measure intern doctors' knowledge, attitudes, and perceptions about antibiotic treatment and determine the situation on the subject.

Methods: A 34-question questionnaire was prepared for the study, and volunteers were administered the questionnaire face-to-face or via a Google form on a mobile WhatsApp application. Prospectively, 221 volunteer physicians participated in the survey, which was conducted between March 15-22, 2024 in Turkey.

Results: Of the participants, 118 (53.4%) were male and 103 (46.6%) were female. The mean age (mean ± SD) was 24 years (24.46±1.83). Many participants had good antibiotic knowledge but a poor antibiotic use percentage. The knowledge that misuse of antibiotics causes resistance was quite high, and there were deficiencies in the mechanisms of resistance. The misconceptions identified were stopping treatment when the clinical condition improved, regardless of the duration, or giving treatment every time the fever was high. There was a significant and positive correlation between age level-antibiotic knowledge and age-level-resistance awareness (rs=0.190, p=0.002 and rs=0.152, p=0.007, respectively). A significant difference was also found between gender-attitude scores (p=0.004). There was a significant (rs=0.247, p=0.003) and positive correlation between antibiotic knowledge and resistance awareness, and a significant (rs=0.610, p<0.001) and positive correlation between antibiotic knowledge and attitude and perception scores.

Conclusion: In order to increase the resistance awareness of the intern doctors and to decrease the wrong attitudes and perceptions, there is a need to develop social programs, practical applications, and patient-oriented practices together with some educational program curriculum changes.

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References

1. World Economic Forum: Global Risks Report 2019. Computer Fraud & Security. 2019: 4 https://doi.org/10.1016/s1361-3723(19)30016-8]

2. Huemer M, Mairpady Shambat S, Brugger SD, Zinkernagel AS. Antibiotic resistance and persistence—Implications for human health and treatment perspectives. EMBO reports. 2020: https://doi.org/10.15252/embr.202051034]

3. Lv L, Wan M, Wang C, Gao X, Yang Q, Partridge SR, Wang Y, Zong Z, Doi Y, Shen J, Jia P, Song Q, Zhang Q, Yang J, Huang X, Wang M, Liu J-H, Bonomo RA. Emergence of a Plasmid-Encoded Resistance-Nodulation-Division Efflux Pump Conferring Resistance to Multiple Drugs, Including Tigecycline, in Klebsiella pneumoniae. mBio. 2020: https://doi.org/10.1128/mBio.02930-19]

4. Tang KWK, Millar BC, Moore JE. Antimicrobial Resistance (AMR). British Journal of Biomedical Science. 2023: https://doi.org/10.3389/bjbs.2023.11387]

5. Affairs. UNDoEaS. The 17 Goals 2023. Available from: https://sdgs.un.org/goals

6. Amanati A, Ayhan M, Coşkun B, Kayaaslan B, Hasanoğlu İ, Kalem AK, Eser F, Bilir YA, Ünlü S, Güner R. Point prevalence of antibiotic usage in major referral hospital in Turkey. Plos One. 2024: https://doi.org/10.1371/journal.pone.0296900]

7. Nandi A, Pecetta S, Bloom DE. Global antibiotic use during the COVID-19 pandemic: analysis of pharmaceutical sales data from 71 countries, 2020–2022. eClinicalMedicine. 2023: https://doi.org/10.1016/j.eclinm.2023.101848]

8. Şencan İ, Çağ Y, Karabay O, Kurtaran B, Güçlü E, Öğütlü A, Demirbaş Z, Bulut D, Eser Karlıdağ G, Sefa Sayar M, Şibar EG, Eren Kutsoylu OÖ, Kul G, Erol S, Bektaş B, Ünver Ulusoy T, Kuzi S, Tasbakan M, Yiğit Ö, Ceran N, İnal AS, Ergen P, Yamazhan T, Uzar H, Ağalar C. Antibiotic use and Influencing Factors Among Hospitalized Patients with COVID-19: A Multicenter Point-Prevalence Study from Turkey. Balkan Medical Journal. 2022: 209 https://doi.org/10.4274/balkanmedj.galenos.2022.2021-11-62]

9. Van Boeckel TP, Pires J, Silvester R, Zhao C, Song J, Criscuolo NG, Gilbert M, Bonhoeffer S, Laxminarayan R. Global trends in antimicrobial resistance in animals in low- and middle-income countries. Science. 2019: https://doi.org/10.1126/science.aaw1944]

10. Cantarero-Arévalo L, Hallas MP, Kaae S. Parental knowledge of antibiotic use in children with respiratory infections: a systematic review. International Journal of Pharmacy Practice. 2017: 31 https://doi.org/10.1111/ijpp.12337]

11. Kotwani A, Joshi PC, Jhamb U, Holloway K. Prescriber and dispenser perceptions about antibiotic use in acute uncomplicated childhood diarrhea and upper respiratory tract infection in New Delhi: Qualitative study. Indian Journal of Pharmacology. 2017: https://doi.org/10.4103/ijp.IJP_508_17]

12. Morley VJ, Firgens EPC, Vanderbilt RR, Zhou Y, Zook M, Read AF, MacGeorge EL. Factors associated with antibiotic prescribing for acute bronchitis at a university health center. BMC Infectious Diseases. 2020: https://doi.org/10.1186/s12879-020-4825-2]

13. Doğan A, Mohamed Alİ A, Abdullahi Alİ M, Orul H. Assessment of tetanus Immunization among healthcare workers in Mogadishu, Somalia. Human Vaccines & Immunotherapeutics. 2023: https://doi.org/10.1080/21645515.2023.2202128]

14. Ahmed H, Bhimani S, Khanum I, Khan A, Khetpal A, Abbas M, Godil F, Godil A, Makhdoom I. Knowledge, attitude and perception survey of doctors regarding antibiotic use and resistance in Karachi, Pakistan. Journal of the Pakistan Medical Association. 2019: https://doi.org/10.5455/jpma.6239]

15. Atif M, Ihsan B, Malik I, Ahmad N, Saleem Z, Sehar A, Babar Z-u-D. Antibiotic stewardship program in Pakistan: a multicenter qualitative study exploring medical doctors’ knowledge, perception and practices. BMC Infectious Diseases. 2021: https://doi.org/10.1186/s12879-021-06043-5]

16. Nabidda S, Ssennyonjo R, Atwaru J, Kanyike AM, Baryayaka S, Pangholi K, Tusiimire J. Antimicrobial resistance and rational prescription practices: knowledge, perceptions and confidence of health profession interns in Uganda. JAC-Antimicrobial Resistance. 2023: https://doi.org/10.1093/jacamr/dlad105]

17. Yuste JR, Matteo AB-D, Gruber F. Impact of Infectious Diseases training in the perception of antibiotic resistance and rational use of antibiotics among Spanish medical students – a cross-sectional study. BMC Medical Education. 2022: https://doi.org/10.1186/s12909-022-03580-8]

18. Correction. BMJ Open Respiratory Research. 2015: https://doi.org/10.1136/bmjresp-2014-000078corr1]

19. Zaidi SF, Alotaibi R, Nagro A, Alsalmi M, Almansouri H, Khan MA, Khan A, Memon I. Knowledge and Attitude Towards Antibiotic Usage: A Questionnaire-Based Survey Among Pre-Professional Students at King Saud bin Abdulaziz University for Health Sciences on Jeddah Campus, Saudi Arabia. Pharmacy. 2020: https://doi.org/10.3390/pharmacy8010005]

20. OECD. 2025. Available from: https://www.oecd.org/turkiye/One-Health-Framework-to-Fight-AMR-T%C3%BCrkiye.pdf.

21. Prevention. CfDCa. Antibiotic resistance threats in the United States. 2025. Available from: https://www.cdc.gov/drugresistance/biggest-threats.html.

22. Jairoun A, Hassan N, Ali A, Jairoun O, Shahwan M, Hassali M.

University students’ knowledge, attitudes, and practice regarding antibiotic use and associated factors: a cross-sectional study in the United Arab Emirates

. International Journal of General Medicine. 2019: 235 https://doi.org/10.2147/ijgm.S200641]

23. Sobierajski T, Mazińska B, Wanke-Rytt M, Hryniewicz W. Knowledge-Based Attitudes of Medical Students in Antibiotic Therapy and Antibiotic Resistance. A Cross-Sectional Study. International Journal of Environmental Research and Public Health. 2021: https://doi.org/10.3390/ijerph18083930]

24. Baddal B, Lajunen TJ, Sullman MJM. Knowledge, attitudes and behaviours regarding antibiotics use among Cypriot university students: a multi-disciplinary survey. BMC Medical Education. 2022: https://doi.org/10.1186/s12909-022-03853-2]

25. Jabbarin H, Nawajah I, Hejaz HA. Knowledge, Attitude, Awareness, and Perceptions among Physicians toward Antibiotic Resistance in Hospitals in South Palestine. Avicenna Journal of Medicine. 2023: 049 https://doi.org/10.1055/s-0043-1764374]

26. Kjærsgaard M, Leth RA, Udupi A, Ank N. Antibiotic stewardship based on education: minor impact on knowledge, perception and attitude. Infectious Diseases. 2019: 753 https://doi.org/10.1080/23744235.2019.1648856]

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