Abstract
Intestinal malrotation is a congenital anomaly commonly occurring in infancy, with adult presentation being rare. The Ladd procedure is the standard treatment for symptomatic malrotation; however, postoperative complications in adults, including obstruction of the second portion of the duodenum (D2), remain poorly characterized, and their etiology may be multifactorial.
A 28-year-old male with chronic gastrointestinal symptoms underwent an elective robotic-assisted laparoscopic Ladd procedure for intestinal malrotation discovered on imaging. He developed persistent high-volume bilious gastric output from postoperative day five; CT and upper GI contrast study failed to identify a transition point. Due to persistent symptoms and radiographic–clinical discordance, esophagogastroduodenoscopy was performed and revealed high-grade narrowing of the second portion of the duodenum. Reoperation revealed dense retroperitoneal fixation precluding safe duodenal mobilization; gastrojejunostomy was performed. Postoperative recovery was complicated by transient dumping syndrome, which improved with dietary modification.
D2 obstruction identified early after the Ladd procedure is rare in adults but should be considered when persistent high-output gastric decompression follows surgery. Whether this obstruction was newly created by surgery or represented a pre-existing congenital abnormality unmasked postoperatively could not be determined, as no baseline assessment of duodenal patency was performed. This case illustrates the potential value of endoscopic evaluation when standard imaging and clinical findings are discordant. Follow-up was limited to two weeks, and longer-term outcome data are needed.
References
1. Alani M, Rentea RM. Midgut Malrotation: StatPearls, Available from: https://www.ncbi.nlm.nih.gov/books/NBK560888, Publishing; 2026.
2. Fu T, Tong WD, He YJ, Wen YY, Luo DL, Liu BH. Surgical management of intestinal malrotation in adults. World J Surg. 2007: 1797 [PMID: 17457643, https://doi.org/10.1007/s00268-007-9018-2]
3. Pickhardt PJ, Bhalla S. Intestinal malrotation in adolescents and adults: spectrum of clinical and imaging features. AJR Am J Roentgenol. 2002: 1429 [PMID: 12438031, https://doi.org/10.2214/ajr.179.6.1791429]
4. Aboagye J, Goldstein SD, Salazar JH, Papandria D, Okoye MT, Al-Omar K, Stewart D, Lukish J, Abdullah F. Age at presentation of common pediatric surgical conditions: Reexamining dogma. J Pediatr Surg. 2014: 995 [PMID: 24888850, https://doi.org/10.1016/j.jpedsurg.2014.01.039]
5. Butterworth WA, Butterworth JW. An adult presentation of midgut volvulus secondary to intestinal malrotation: A case report and literature review. Int J Surg Case Rep. 2018: 46 [PMID: 30077833, https://doi.org/10.1016/j.ijscr.2018.07.007]
6. Matzke GM, Dozois EJ, Larson DW, Moir CR. Surgical management of intestinal malrotation in adults: comparative results for open and laparoscopic Ladd procedures. Surg Endosc. 2005: 1416 [PMID: 16151680, https://doi.org/10.1007/s00464-004-8249-7]
7. Mitsunaga T, Saito T, Terui K, Nakata M, Ohno S, Mise N, Oita S, Yoshida H. Risk Factors for Intestinal Obstruction After Ladd Procedure. Pediatr Rep. 2015: 5795 [PMID: 26266030, https://doi.org/10.4081/pr.2015.5795]
8. Nehra D, Goldstein AM. Intestinal malrotation: varied clinical presentation from infancy through adulthood. Surgery. 2011: 386 [PMID: 20719352, https://doi.org/10.1016/j.surg.2010.07.004]
9. Lieu DQ, Dung TN, Long TB, Anh TN, Dung LQ, Duc NM. A rare case of Ladd's band causing duodenal occlusion in an adult with intestinal malrotation. Radiol Case Rep. 2023: 3735 [PMID: 37636537, https://doi.org/10.1016/j.radcr.2023.08.001]
10. Applegate KE, Anderson JM, Klatte EC. Intestinal malrotation in children: a problem-solving approach to the upper gastrointestinal series. Radiographics. 2006: 1485 [PMID: 16973777, https://doi.org/10.1148/rg.265055167]
11. Fatehi Hassanabad A, Zarzycki AN, Jeon K, Deniset JF, Fedak PWM. Post-Operative Adhesions: A Comprehensive Review of Mechanisms. Biomedicines. 2021: [PMID: 34440071, https://doi.org/10.3390/biomedicines9080867]
12. Mizuta N, Kikuchi T, Fukuda Y. Adult Intestinal Malrotation Treated with Laparoscopic Ladd Procedure. Case Rep Surg. 2022: 6874885 [PMID: 36304201, https://doi.org/10.1155/2022/6874885]
13. Akomea-Agyin E, Agbedinu K, Dally CK, Galley F, Kankam EO, Banini GE. Duodenal stenosis in adult malrotation: When Ladd procedure is not enough: A case report. Int J Surg Case Rep. 2024: 109713 [PMID: 38703614, https://doi.org/10.1016/j.ijscr.2024.109713]
14. Mustaqim K, Mohd Shah MS, Muhammad Asri NA. Double Whammy: Duodenal Stenosis and Gastrointestinal Malrotation. Cureus. 2023: e36137 [PMID: 37065346, https://doi.org/10.7759/cureus.36137]
15. Riley DS, Barber MS, Kienle GS, Aronson JK, von Schoen-Angerer T, Tugwell P, Kiene H, Helfand M, Altman DG, Sox H, Werthmann PG, Moher D, Rison RA, Shamseer L, Koch CA, Sun GH, Hanaway P, Sudak NL, Kaszkin-Bettag M, Carpenter JE, Gagnier JJ. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017: 218 [PMID: 28529185, https://doi.org/10.1016/j.jclinepi.2017.04.026]

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Copyright (c) 2026 Akram Alnounou, DO, Ajay Katwala, Bisher Sawaf, MD, MSc, Arghyadeep Ganguly, MD, Yusuf Hallak, MD

