Abstract
Hyponatremia is a common electrolyte abnormality that can lead to various complications, including rhabdomyolysis. Observational studies have identified a correlation between hyponatremia and the occurrence of rhabdomyolysis in hospitalized patients. We report a 45-year-old male with a medical history of hypertension, hyperlipidemia, and a congenital neurological defect featuring an 8 cm right frontal porencephalic cyst communicating with the right lateral ventricle, colpocephaly, congenital left hemiparesis, paranoid schizophrenia, anxiety, and depression. He presented with rhabdomyolysis caused by hyponatremia and aggravated by psychogenic polydipsia. A hyponatremic state caused by psychogenic polydipsia may induce rhabdomyolysis in patients with a genetic predisposition. Hence, monitoring muscle markers in these patients is crucial, with further evidence needed to establish hyponatremia as the primary cause of rhabdomyolysis in the absence of other confounders.
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