Vol. 2 No. 3 (2026)

ASIDE Gastroenterology Vol. 2, No. 3 (August 1, 2026) presents a clinically focused collection of original research and narrative reviews spanning gastrointestinal bleeding, acute cholangitis, gastrointestinal oncology, advanced endoscopic therapy, and health equity in metabolic liver disease. The issue includes a retrospective cohort study examining the timing of esophagogastroduodenoscopy in adults aged 75 years and older with upper gastrointestinal bleeding, reporting no clear difference in short-term outcomes between early and delayed endoscopy while emphasizing the limitations of low event counts and potential selection bias. A national inpatient analysis evaluates inter-hospital transfer among patients hospitalized with acute cholangitis, demonstrating greater illness severity and resource utilization among transferred patients without a statistically significant independent association with adjusted in-hospital mortality. The issue also features a narrative review of early palliative care in gastrointestinal oncology, highlighting needs-based and diagnosis-anchored referral models that support symptom management, communication, and patient-centered decision-making. Another review compares endoscopic vacuum therapy with self-expanding metal stents for upper gastrointestinal transmural defects, critically examining the substantial overlap among existing meta-analyses and the low-certainty observational evidence supporting current practice. Completing the issue is a United States–focused review of racial and ethnic disparities across the MASLD/MASH care continuum, addressing differences in disease burden, diagnostic accuracy, clinical-trial representation, access to emerging pharmacotherapies, and liver transplantation. Collectively, this issue reinforces ASIDE Gastroenterology’s commitment to evidence-based clinical care, methodological transparency, equitable healthcare delivery, and meaningful advances in gastroenterology and hepatology.