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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">aside-hs</journal-id>
      <journal-title-group>
        <journal-title>ASIDE Health Sciences</journal-title>
      </journal-title-group>
      <issn pub-type="ppub">3067-8730</issn>
      <issn pub-type="epub">3067-8749</issn>
      <publisher>
        <publisher-name>PubPorta Publishing LLC</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.71079/ASIDE.HS.042826665</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Review Article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Ocular Trauma Patterns in the Middle East and North Africa: A Scoping Review with Emphasis on Iraq</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" id="contrib-d95bac0921ff">
          <name>
            <surname>Abbas</surname>
            <given-names>Elaf Falih</given-names>
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        <contrib contrib-type="author" id="contrib-8b042345363f">
          <name>
            <surname>Imran</surname>
            <given-names>Mohammed Mousa</given-names>
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          <contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-0804-8520</contrib-id>
          <name>
            <surname>Saleh</surname>
            <given-names>Mustafa Yahya</given-names>
          </name>
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          <contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5809-5087</contrib-id>
          <name>
            <surname>Omran</surname>
            <given-names>Huda</given-names>
          </name>
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          <email>hudamossa.omran@gmail.com</email>
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      <aff id="aff1">
        <institution>Ophthalmology Department, AlSader Teaching Hospital, Basra</institution>
        <country>Iraq</country>
      </aff>
      <aff id="aff2">
        <institution>Genetic Department, Aldafter Medical Center, Arabian Gulf University, Manama</institution>
        <country>Bahrain</country>
      </aff>
      <author-notes>
        <corresp id="cor1">Corresponding author. E-mail: <email>hudamossa.omran@gmail.com</email></corresp>
        <fn fn-type="coi-statement">
          <p>The authors declare that they have no known financial, personal, professional, or institutional relationships that could have influenced, or could be perceived to have influenced, the work reported in this manuscript. The authors further confirm that there are no competing interests related to the study design, literature selection, interpretation of findings, manuscript preparation, or decision to submit this article for publication.</p>
        </fn>
      </author-notes>
      <pub-date publication-format="electronic" date-type="pub" iso-8601-date="2026-04-28">
        <day>28</day>
        <month>04</month>
        <year>2026</year>
      </pub-date>
      <pub-date publication-format="electronic" date-type="collection" iso-8601-date="2026">
        <year>2026</year>
      </pub-date>
      <volume>2</volume>
      <issue>2</issue>
      <fpage>40</fpage>
      <lpage>46</lpage>
      <history>
        <date date-type="received" iso-8601-date="2026-03-15">
          <day>15</day>
          <month>03</month>
          <year>2026</year>
        </date>
        <date date-type="rev-recd" iso-8601-date="2026-04-18">
          <day>18</day>
          <month>04</month>
          <year>2026</year>
        </date>
        <date date-type="accepted" iso-8601-date="2026-04-26">
          <day>26</day>
          <month>04</month>
          <year>2026</year>
        </date>
      </history>
      <permissions>
        <copyright-year>2026</copyright-year>
        <copyright-holder>Elaf Falih Abbas, Mohammed Mousa Imran, Mustafa Yahya Saleh, Huda Omran</copyright-holder>
        <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0">
          <license-p>This is an open-access article.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>Background: Ocular injury is one of the leading causes of preventable monocular blindness globally. These injuries have multiple etiologies, with socioeconomic factors and geopolitical instability as the main drivers. A unique combination of these factors can be seen in the MENA region.</p>
        <p>Methods: This scoping review used a structured analysis of published research. We searched PubMed and Scopus (2004–2025) using terms for ocular trauma and MENA countries. Two reviewers independently screened titles, abstracts, and full texts against predefined inclusion criteria that accepted original research, reviews, and case series; a third reviewer resolved disagreements. Data were extracted using a standardized form and synthesized descriptively. No formal quality appraisal was performed.</p>
        <p>Results: The search identified 918 records, of which 25 were included. Etiological patterns differed markedly across countries. In Iraq, conflict-related mechanisms (blasts, bullets) dominated in military cohorts, alongside civilian motorcycle accidents. In other MENA countries, road traffic accidents and occupational injuries were more frequently reported. Management challenges in Iraq were compounded by limited primary eye care infrastructure and high rates of enucleation. Pediatric trauma was also a major concern. Population‑based civilian data from conflict‑affected settings remain scarce.</p>
        <p>Conclusion: Ocular trauma is a major health issue in Iraq, with patterns suggesting an association with decades of conflict. However, population‑based comparative data are very limited. This scoping review highlights evidence gaps, particularly the scarcity of population-based civilian data from conflict-affected settings.</p>
      </abstract>
      <kwd-group>
        <kwd>Ocular Trauma</kwd>
        <kwd>War Injuries</kwd>
        <kwd>Blindness</kwd>
        <kwd>MENA</kwd>
        <kwd>Iraq</kwd>
        <kwd>Scoping Review</kwd>
      </kwd-group>
      <funding-group>
        <funding-statement>The authors declare that no specific grant or funding was received for this research from any public, commercial, or not-for-profit funding agency.</funding-statement>
      </funding-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec-22ce1a8b8631">
      <title>Introduction</title>
      <p id="blk-416b2e6e5b3b">Ocular trauma is a critical public health problem, accounting for a substantial proportion of monocular blindness worldwide. It significantly affects individual quality of life, reducing their economic productivity and increasing healthcare costs.</p>
      <p id="blk-f7721d6771f8">The pattern of injury is largely linked to the local environment, culture, industry, and safety standards. The MENA region, with its vast geographic and political diversity, offers a critical lens for examining these relationships. While countries in the Gulf Cooperation Council (GCC) have advanced rapidly in healthcare, including ophthalmic care, others deal with the aftermath of conflict, economic instability, and limited healthcare resources. Iraq stands out within this continuum, having endured decades of war, economic sanctions, and internal conflict. The ophthalmological consequences of this are severe and distinct.</p>
      <p id="blk-4fcabcf265d7">This review aims to evaluate the available scientific literature on ocular trauma in the MENA region by comparing the etiological factors and management challenges in Iraq with those of neighboring countries. Based on the available evidence, we interpret that prolonged conflict in Iraq is associated with a distinct profile of severe ocular injuries and treatment needs, though population-based comparative data remain limited.</p>
    </sec>
    <sec id="sec-53feb6310e93">
      <title>Methods</title>
      <sec id="sec-cf6c5847794a">
        <title>Study Design and Selection</title>
        <p id="blk-90a7c3e3595d">This review was conducted as a scoping review following the framework of Arksey and O’Malley and reported in accordance with the PRISMA ScR (Preferred Reporting Items for Systematic Reviews and Meta Analyses extension for Scoping Reviews) checklist. A protocol was not registered. We searched PubMed and Scopus for articles published between January 2004 and June 2025. An initial PubMed search identified relevant keywords. These were used in a systematic search strategy that combined free-text and Boolean terms applied to both databases. These search terms for ocular trauma and MENA countries included the following:</p>
        <p id="blk-5b31d040b556">Two reviewers independently screened titles and abstracts, followed by full-text review. A third reviewer resolved disagreements. The inclusion criteria were original research, reviews, and case series in English reporting on the etiology, epidemiology, or management of ocular trauma in MENA countries. Exclusion criteria: non-English publications, studies not focused on trauma, editorials, preclinical studies, and studies conducted outside the MENA region.</p>
        <p id="blk-f5cd1184f98c">Articles were systematically grouped by their primary country or region of focus, primary mechanism of injury (e.g., blast, road traffic accidents RTA, occupational), and key clinical themes (e.g., pediatric trauma, surgical outcomes, rehabilitation). Data relevant to Iraq were extracted and analyzed in parallel with data from other MENA nations, like Iran, Saudi Arabia, and Jordan, to enable a direct comparative analysis of epidemiological patterns, management protocols, and public health implications.</p>
      </sec>
      <sec id="sec-755fe4eada49">
        <title>Data Extraction and Synthesis</title>
        <p id="blk-d4c1bf4ca818">Microsoft Excel was used to manage extracted data. Authors, year, country, study design, population (civilian, military, or mixed), primary injury mechanism, and key clinical findings were collected. Data were grouped by country <xref ref-type="fig" rid="fig-1"/>. Given heterogeneity in study designs and population, no meta-analysis was performed. Synthesis is descriptive and comparative. All included studies were summarized in a single table <xref ref-type="table" rid="tbl-2"/>. Risk of bias assessment was not performed, consistent with scoping review methodology. Findings were presented as descriptive patterns rather than definitive comparative epidemiology.</p>
      </sec>
    </sec>
    <sec id="sec-e693b4939d02">
      <title>Results</title>
      <p id="blk-53e1229e0043">The initial search yielded 918 records. After duplications had been removed, 600 titles and abstracts were screened, and 486 were excluded. The full text of 114 articles was assessed for eligibility. A total of 25 studies from the MENA region met the inclusion criteria and were included in the qualitative synthesis <xref ref-type="fig" rid="fig-1"/>. Of the 25 included studies, 11 focused on Iraq (including those that covered both Iraq and Afghanistan), 3 on Iran, 1 on Saudi Arabia, 1 on Jordan, 2 on Palestine/Gaza, 1 on the Levant, 1 on Turkey, and 1 examined the MENA region as a whole. Several studies involved military personnel, while others focused on civilian or pediatric populations. To ensure transparency, the evidence is presented in two tiers: primary epidemiologic studies (cross sectional, cohort, and case series reporting original trauma data) form the basis for all comparative statements about injury mechanisms, severity, and outcomes. Reviews, meta-analyses, and service-oriented papers are cited only for contextual background (e.g., infrastructure or rehabilitation discussions) and are not used for direct epidemiological comparisons.</p>
      <p id="blk-7ed747305997">Epidemiological patterns and etiological comparison The etiology of ocular trauma in MENA is a direct reflection of local realities. The provided literature reveals a clear contrast between conflict-affected zones like Iraq and more stable regions. As shown in Table 1.</p>
      <p id="blk-ba411164391d">While Iraq represents an extreme within the conflict injury spectrum, a gradient of instability and resource scarcity exists across the region.</p>
      <p id="blk-db7011d7ffe9">The data from Iraq is affected by the consequences of modern conflicts. Studies on military personnel from Operation Iraqi Freedom detail high rates of open globe wounds from blast and fragmentation injuries [<sup><xref ref-type="bibr" rid="ref-d349ef5323f4">1</xref></sup>,<sup><xref ref-type="bibr" rid="ref-4572a4cffddf">2</xref></sup>]. A study by Justin and his coworkers of U.S. personnel evacuated to a tertiary military hospital from Iraq (2001 – 2011) found that orbital fractures occurred in 34.2% (304/890) of eye injuries, with 31.3% (95/304) of those cases resulting in no light perception [<sup><xref ref-type="bibr" rid="ref-21682b9a798d">3</xref></sup>]. Earlier data from the 2003 – 2005 periods documented 797 severe eye injuries, which included 438 open globe injuries (49 bilateral) and 116 eyes requiring removal (enucleation/evisceration) [<sup><xref ref-type="bibr" rid="ref-913077477198">4</xref></sup>]. Concurrently, civilian studies point to motorcycle accidents as a major cause [<sup><xref ref-type="bibr" rid="ref-4a74784a9471">5</xref></sup>] of ocular morbidity, suggesting a dual burden of conflict-related and conventional trauma. Hashim and his collaborators documented that Iraqi tertiary hospitals reported 335 ophthalmological accidents from motorcycle crashes, predominantly affecting young males (mean age 27.8 years) [<sup><xref ref-type="bibr" rid="ref-4a74784a9471">5</xref></sup>]. Injuries were classified as mild in 55.82%, moderate in 27.16%, and severe in 17.01% of cases, with lid lacerations (60.9%) and corneoscleral injuries (22.1%) being most common [<sup><xref ref-type="bibr" rid="ref-4a74784a9471">5</xref></sup>].</p>
      <p id="blk-970cbcd518c1">In contrast, studies from other regions highlight different priorities. Occupational hazards are prominent, including industrial accidents and olive-harvesting injuries in the Levant [<sup><xref ref-type="bibr" rid="ref-42813c406de8">6</xref></sup>]. RTA is a universal cause, detailed in studies from Iran [<sup><xref ref-type="bibr" rid="ref-0a14d18a7085">7</xref></sup>] and Saudi Arabia [<sup><xref ref-type="bibr" rid="ref-ff94b27465e6">8</xref></sup>]. Unique environmental injuries include prickly pear spine keratoconjunctivitis in Jordan [<sup><xref ref-type="bibr" rid="ref-620b07c30f5a">9</xref></sup>] and fireworks injuries during celebrations in Saudi Arabia [<sup><xref ref-type="bibr" rid="ref-a20dbc4df9fa">10</xref></sup>]. Terror related ocular trauma is reported from a tertiary center in Saudi Arabia [<sup><xref ref-type="bibr" rid="ref-d6c9d437c0b2">11</xref></sup>], indicating the high rate of ocular trauma in conflict affected settings; similar patterns are observed in Gaza [<sup><xref ref-type="bibr" rid="ref-bbb8e92a1821">12</xref></sup>,<sup><xref ref-type="bibr" rid="ref-632b917186ce">13</xref></sup>]. Challa and Al Rasheed linked refractive error and abnormal stereopsis among truck drivers in Saudi Arabia to the risk of road traffic accidents, adding depth to the understanding of RTA etiologies [<sup><xref ref-type="bibr" rid="ref-ff94b27465e6">8</xref></sup>]. This variation in the etiology of ocular trauma, from high-velocity conflict-related injuries to occupational and environmental mechanisms, directly influences the spectrum of injury severity, clinical presentation, and subsequent management challenges encountered across the region. These relationships between cause and clinical consequence are explored in the following section. The variation in the etiology of ocular trauma is illustrated in <xref ref-type="fig" rid="fig-2"/>.</p>
      <sec id="sec-9cf459d72713">
        <title>Disparities in Clinical Management and Visual Prognosis</title>
        <p id="blk-08b91a15e2b1">The nature of trauma determines its severity. Iraqi data emphasize high energy, devastating injuries often presenting with extensive tissue loss, multiple intraocular foreign bodies, and associated maxillofacial trauma [<sup><xref ref-type="bibr" rid="ref-e31e63155bc8">14</xref></sup>,<sup><xref ref-type="bibr" rid="ref-4572a4cffddf">2</xref></sup>]. In Iraq, the capacity to manage this trauma burden is severely constrained. A study revealed that only 2% of Iraq’s primary health centers offer eye-related services, which contributes to tertiary hospitals being overwhelmed; more than half of specialist hospital consultations are for conditions that are manageable at the primary level [<sup><xref ref-type="bibr" rid="ref-e1072f04fdbe">15</xref></sup>]. This systemic gap takes place in the context of a high overall burden of eyesight loss in Iraq (7.4% of Iraqis, all causes combined, including cataract, glaucoma, and trauma [<sup><xref ref-type="bibr" rid="ref-339b1719a68a">16</xref></sup>,<sup><xref ref-type="bibr" rid="ref-e1072f04fdbe">15</xref></sup>]), which is provided here only as background on the general eye health challenge.</p>
        <p id="blk-ff8c13b90243">In other MENA settings, presentations, while serious, may more frequently involve isolated corneal abrasions, lid lacerations, or blunt trauma. <xref ref-type="fig" rid="fig-3"/> shows the different kinds of trauma reported in many studies included in this review and reflects the variation in clinical courses and, consequently, the treatment needed.</p>
        <p id="blk-b131bcbe37a2">The surgical burden differs accordingly. Evisceration and enucleation rates are significantly reported in the context of military trauma from Iraq [<sup><xref ref-type="bibr" rid="ref-088698c2367d">17</xref></sup>,<sup><xref ref-type="bibr" rid="ref-913077477198">4</xref></sup>] and in Palestinian territories [<sup><xref ref-type="bibr" rid="ref-bbb8e92a1821">12</xref></sup>], reflecting the severity of initial injuries and possibly delayed presentation. Surgical innovation is directed at complex reconstruction, such as managing orbital bullet injuries [<sup><xref ref-type="bibr" rid="ref-4572a4cffddf">2</xref></sup>] and repairing corneal perforations using advanced techniques like the “sandwich” and amniotic membrane transplantation [<sup><xref ref-type="bibr" rid="ref-6294b07cb0c7">18</xref></sup>]. Managing sequelae like traumatic cataract and preventing sympathetic ophthalmia are critical concerns shared across the region [<sup><xref ref-type="bibr" rid="ref-2d2e874ac634">19</xref></sup>] An important and recurrent theme is the high incidence of trauma among children, a vulnerable demographic across the MENA region. Ocular injury is a leading cause of preventable blindness in children all over the world. Studies from Iraq [<sup><xref ref-type="bibr" rid="ref-82fd06b0fa6d">20</xref></sup>], Iran [<sup><xref ref-type="bibr" rid="ref-cb7642d2f672">21</xref></sup>], and Saudi Arabia [<sup><xref ref-type="bibr" rid="ref-5734b8c91047">22</xref></sup>] consistently show that children represent a vulnerable demographic, suffering from domestic accidents and stray projectile injuries, often leading to lifelong visual disability and a need for prosthetic fitting.</p>
        <p id="blk-e43cddb2b914">The demand for pediatric prostheses following enucleation and evisceration was highlighted with this permanent need [<sup><xref ref-type="bibr" rid="ref-632b917186ce">13</xref></sup>]. The challenges of delivering pediatric ophthalmic care in Gaza highlight how systemic collapse in conflict zones exacerbates trauma outcomes [<sup><xref ref-type="bibr" rid="ref-632b917186ce">13</xref></sup>]. Furthermore, a study by Bahremani and colleagues confirmed that, while the prevalence of vision loss in MENA decreased by 11.1% from 1990 to 2019, the absolute number remains high at 32.5 million cases, with Iraq’s age-standardized prevalence rate at 7188.6 per 100,000 [<sup><xref ref-type="bibr" rid="ref-339b1719a68a">16</xref></sup>].</p>
        <p id="blk-a41e1f905275">Furthermore, research on Iranian chemical warfare survivors provides clear evidence of the significant reduction in quality of life associated with ophthalmologic war injuries [<sup><xref ref-type="bibr" rid="ref-855731d3318b">23</xref></sup>], a finding with direct relevance to the Iraqi civilian population [<sup><xref ref-type="bibr" rid="ref-49b45bb265f6">24</xref></sup>,<sup><xref ref-type="bibr" rid="ref-f95f2ab5e0b0">25</xref></sup>].</p>
      </sec>
      <sec id="sec-858b9004d390">
        <title>Public Health Implications and Challenges</title>
        <p id="blk-2b3590275306">A distinguished variation exists between the advanced, well-resourced tertiary eye centers in the Gulf countries and the overwhelmed or fragmented systems in conflict zones. The Iraqi healthcare system bears a double burden: managing acute, complex war injuries requiring multi-specialty input and providing lifelong rehabilitation for survivors [<sup><xref ref-type="bibr" rid="ref-4572a4cffddf">2</xref></sup>]. This includes not only prosthetic services but also low vision aid, psychological support for disfigurement and vision loss, and surgical management of late complications like glaucoma and retinal detachment. The strain on specialized ophthalmic surgical capacity is huge, Gaza, for example [<sup><xref ref-type="bibr" rid="ref-bbb8e92a1821">12</xref></sup>]. This disparity affects everything from timely primary repair to access to complex vitreoretinal surgery.</p>
      </sec>
      <sec id="sec-145dbbad9000">
        <title>Etiology Specific Prevention Strategies</title>
        <p id="blk-87ed6d23259d">For Iraq, the primary preventive strategy is primarily political, focusing on conflict mitigation, mine clearance, and weapons control. Secondary prevention includes disseminating basic ocular first-aid knowledge to first responders and the public, and strengthening emergency trauma systems.</p>
        <p id="blk-93f877a20bff">For other countries in the MENA region, effective strategies include enforcing occupational safety laws (e.g., mandatory eye protection in agriculture/industry), strict RTA prevention campaigns, public awareness on domestic hazards (fireworks, hazardous toys, chemicals), and community education on the dangers of traditional eye remedies.</p>
      </sec>
      <sec id="sec-1b9b5b1729e3">
        <title>Limitations and Future Directions</title>
        <p id="blk-e99c048c96df">The nature of its source data limits this review. The dataset consists of English-language, predominantly hospital-based studies, which introduces publication bias and underrepresents cases that do not reach tertiary centers. There is an obvious scarcity of population-based incidence and prevalence studies from Iraq.</p>
        <p id="blk-6ef000d8a3cc">Future research efforts must prioritize several key directions to address the identified gaps. First, establishing standardized ocular trauma registries in Iraq is essential for capturing accurate national epidemiological data. Building on this foundation, conducting cost-effectiveness analyses of prevention strategies tailored to the Iraqi context, compared with other MENA countries, would help guide efficient resource allocation. Additionally, research is needed to develop and evaluate integrated care models capable of delivering proper ophthalmic trauma and rehabilitation services within resource-constrained, post-conflict primary health systems.</p>
      </sec>
    </sec>
    <sec id="sec-2d16fcef4660">
      <title>Conclusion</title>
      <p id="blk-d4df0b381566">The etiology of ocular trauma in the MENA region is a potent indicator of its socioeconomic and political conditions. From workplace accidents to high-velocity traumas, Iraq presents itself as a significant case study in this review. The patterns observed suggest the long-term ophthalmological consequences of decades of conflict manifesting as a high volume of severe, sight-depriving injuries and a legacy of rehabilitation needs. Without population-based data, the full clinical burden of ocular trauma in conflict-affected communities remains undetermined.</p>
    </sec>
  </body>
  <back>
    <ack>
      <title>Acknowledgments</title>
      <p>None.</p>
    </ack>
    <sec sec-type="ethics-statement">
      <title>Institutional Review Board (IRB)</title>
      <p>This study is a scoping review of previously published literature and did not involve direct interaction with human participants, collection of identifiable private information, intervention on patients, or use of unpublished patient-level data. Therefore, institutional review board approval was not required. Informed consent was also not applicable.</p>
    </sec>
    <sec sec-type="ai-statement">
      <title>Large Language Model</title>
      <p>During the preparation of this manuscript, the authors used ChatGPT (OpenAI) to assist in refining English-language writing and enhancing <xref ref-type="fig" rid="fig-2"/> and <xref ref-type="fig" rid="fig-3"/>. The tool was used solely for language improvement and visual clarity; AI generated no scientific content, data, or conclusions. The authors take full responsibility for the integrity and accuracy of the manuscript.</p>
    </sec>
    <sec sec-type="author-contributions">
      <title>Authors Contribution</title>
      <p>EA contributed to conceptualization, methodology, validation, formal analysis, resources, writing review and editing, and supervision. MI contributed to conceptualization, methodology, validation, formal analysis, resources, writing original draft preparation, writing review and editing, and visualization. MS contributed to methodology, validation, formal analysis, resources, and writing review and editing. HO contributed to conceptualization, validation, formal analysis, resources, writing original draft preparation, writing review and editing, and visualization. All authors have read and agreed to the published version of the manuscript.</p>
    </sec>
    <sec sec-type="data-availability">
      <title>Data Availability</title>
      <p>No new primary data were generated in this scoping review. All data synthesized in this article were derived from previously published studies identified through PubMed and Scopus searches and from the sources cited in the reference list.</p>
    </sec>
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  <floats-group>
    <fig id="fig-1" specific-use="aside-float: width=full-width; anchor=blk-d4c1bf4ca818" position="float">
      <label>Figure 1</label>
      <caption>
        <p>PRISMA flow diagram for the identification and selection of studies eligible for this review.</p>
      </caption>
      <graphic xlink:href="1.jpg"/>
    </fig>
    <fig id="fig-2" specific-use="aside-float: width=full-width; anchor=blk-ba411164391d" position="float">
      <label>Figure 2</label>
      <caption>
        <p>Schematic illustration of key etiological factors and patterns of ocular trauma.</p>
      </caption>
      <graphic xlink:href="2.jpg"/>
    </fig>
    <fig id="fig-3" specific-use="aside-float: width=full-width; anchor=blk-b131bcbe37a2" position="float">
      <label>Figure 3</label>
      <caption>
        <p>Schematic illustration of trajectories and clinical sequelae of ocular injury.</p>
      </caption>
      <graphic xlink:href="3.jpg"/>
    </fig>
    <table-wrap id="tbl-1" specific-use="aside-float: layout=full-width; longtable=1; anchor=blk-ba411164391d" position="float">
      <label>Table 1</label>
      <caption>
        <p>Comparison of Ocular Trauma Epidemiology Across Countries/Regions in the MENA Region (n = 25) Tier 1 (primary epidemiologic) studies are marked with †.</p>
      </caption>
      <table>
        <thead>
          <tr id="row-ca253f26d6a7">
            <th id="cell-7ee9600c94ef">
              <bold>Author(s), Year</bold>
            </th>
            <th id="cell-8cc03bec73b3">
              <bold>Country/ Region</bold>
            </th>
            <th id="cell-22be2f4cd321">
              <bold>Study Design</bold>
            </th>
            <th id="cell-7b6240f2123e">
              <bold>Sample Size (N)</bold>
            </th>
            <th id="cell-e35e8647afc9">
              <bold>Study Setting</bold>
            </th>
            <th id="cell-09c0f7ab3f8a">
              <bold>Denominator / Population at Risk</bold>
            </th>
            <th id="cell-913780ab2006">
              <bold>Population</bold>
            </th>
            <th id="cell-99340751f39d">
              <bold>Primary Mechanism(s)</bold>
            </th>
            <th id="cell-cd1c173a956d">
              <bold>Key Findings</bold>
            </th>
          </tr>
        </thead>
        <tbody>
          <tr id="row-acb3a9ed2f89">
            <td id="cell-f1a2e67b519c">Sulaiman II et al., 2024</td>
            <td id="cell-b0593091796b">Iraq</td>
            <td id="cell-66fa6f942743">Review/meta-analysis (Tier 2)</td>
            <td id="cell-d2f5622ed674">688</td>
            <td id="cell-783de9e0869e">Military &amp; civilian hospitals</td>
            <td id="cell-6420e103a9b6">Not applicable</td>
            <td id="cell-34155112698f">Civilian/ military</td>
            <td id="cell-5c31741b30ec">Ballistic</td>
            <td id="cell-8f513d314d2f">High enucleation rates; penetrating orbital trauma</td>
          </tr>
          <tr id="row-510b644a39d4">
            <td id="cell-4553963e14ce">Blanch RJ et al., 2011†</td>
            <td id="cell-6c041de5a905">Iraq</td>
            <td id="cell-28b4ddef2b6b">Case series</td>
            <td id="cell-efda7d562852">63</td>
            <td id="cell-7724b33ffd39">British military hospital (Iraq/Afghanistan)</td>
            <td id="cell-e328a32b0884">All combat eye injuries referred</td>
            <td id="cell-037b88faa8d8">Military personnel</td>
            <td id="cell-6f9652a92993">Blast/ fragmentation</td>
            <td id="cell-144854a0f2fc">52% open globe</td>
          </tr>
          <tr id="row-f81bed8c8e81">
            <td id="cell-d5ef3ecbf1d0">Justin GA et al., 2020†</td>
            <td id="cell-29b254b2c2b4">Iraq</td>
            <td id="cell-931c3a665931">Cohort</td>
            <td id="cell-5192c1bcf02a">652</td>
            <td id="cell-1ff833c5068b">U.S. military tertiary hospital</td>
            <td id="cell-3493b5a4a626">All orbital fractures referred</td>
            <td id="cell-7026a4a2efc4">Military personnel</td>
            <td id="cell-743bc2ed5639">Blast</td>
            <td id="cell-8f6b7fef84f9">31.3% NLP</td>
          </tr>
          <tr id="row-552970e9d0b6">
            <td id="cell-12e877cbf2f1">Thach AB et al., 2008†</td>
            <td id="cell-995c040972dd">Iraq</td>
            <td id="cell-8e55b001c5f1">Case series</td>
            <td id="cell-d88cdd101160">797 severe eye injuries</td>
            <td id="cell-3c98f43e232a">U.S. military registry</td>
            <td id="cell-5d92786019aa">Combat zone injuries 2003–2005</td>
            <td id="cell-9fe4c5514876">Military personnel</td>
            <td id="cell-b38e32ffb891">Blast/ fragmentation</td>
            <td id="cell-8394b59c57d2">116 enucleations; 438 open globe</td>
          </tr>
          <tr id="row-22a1b2b933bd">
            <td id="cell-d4de8c998b03">Hashim ZA et al., 2024†</td>
            <td id="cell-1ec87526bb4f">Iraq</td>
            <td id="cell-912a64eab979">Cross sectional</td>
            <td id="cell-ae3eac7368c4">335</td>
            <td id="cell-38230ce3820c">Iraqi tertiary hospitals</td>
            <td id="cell-1bbc0417a7e0">Consecutive motorcycle accident patients</td>
            <td id="cell-7b6727ecfec9">Civilian</td>
            <td id="cell-195947b58fa2">Motorcycle accidents</td>
            <td id="cell-a7464dcaeb76">17% severe; lid/corneoscleral injuries</td>
          </tr>
          <tr id="row-d5f7a7322ebd">
            <td id="cell-c0d610d0397e">Yulish M et al., 2012†</td>
            <td id="cell-ce822fdefbe7">Levant</td>
            <td id="cell-8299042c14f0">Case series</td>
            <td id="cell-e9f7f3e15e30">119</td>
            <td id="cell-a606e8965d0b">Regional hospital</td>
            <td id="cell-aae359b628cb">Agricultural workers presenting with eye injury</td>
            <td id="cell-df156e5d5d61">Agricultural workers</td>
            <td id="cell-fe5af6415d64">Olive harvesting</td>
            <td id="cell-bee6ba0277a0">Corneal perforations</td>
          </tr>
          <tr id="row-a57d3945bc2f">
            <td id="cell-69ad7ddfa486">Hashemi H et al., 2015†</td>
            <td id="cell-a0992127a416">Iran</td>
            <td id="cell-095b8136ef36">Cross sectional</td>
            <td id="cell-2eaa78317a0b">5190</td>
            <td id="cell-2c05224a627b">Population based</td>
            <td id="cell-5da3b6f7ce33">General population aged 40–64</td>
            <td id="cell-f6bfd413dbac">Civilian</td>
            <td id="cell-9857edf64d64">Mixed</td>
            <td id="cell-833566ff9136">Lifetime trauma prevalence 8.57% (blunt 3.91%, sharp 3.82%, chemical 1.93%)</td>
          </tr>
          <tr id="row-cc054d1c20c7">
            <td id="cell-27bcc490202e">Challa NK et al., 2024†</td>
            <td id="cell-3699fc5aa257">Saudi Arabia</td>
            <td id="cell-e0f65a1450c8">Cross sectional</td>
            <td id="cell-af4e8b1290da">300 truck drivers</td>
            <td id="cell-6acb4e1cf863">Truck driving company</td>
            <td id="cell-73b39b1626f2">All active drivers</td>
            <td id="cell-6a3926979f66">Civilian</td>
            <td id="cell-a00e25b549ab">RTA</td>
            <td id="cell-ef689ecc94b6">Refractive error linked to RTA risk</td>
          </tr>
          <tr id="row-329a16e5c3b4">
            <td id="cell-08d8f39aef3a">Odat TAM et al., 2014†</td>
            <td id="cell-938a6b22f414">Jordan</td>
            <td id="cell-2f4b15823bbd">Case series</td>
            <td id="cell-426c16fd0559">21</td>
            <td id="cell-8dd92e4a3779">Tertiary eye center</td>
            <td id="cell-56e1d73a08d3">Consecutive cases</td>
            <td id="cell-a78964e9190c">Civilian</td>
            <td id="cell-1e78ae304970">Prickly pear spine</td>
            <td id="cell-d0a498428186">Keratoconjunctivitis</td>
          </tr>
          <tr id="row-b6b9a39405bc">
            <td id="cell-69016ce28d6b">Al Barqi M et al., 2022†</td>
            <td id="cell-6ac9c969826a">Saudi Arabia</td>
            <td id="cell-7f0f3f4c450f">Case series</td>
            <td id="cell-e9ff6654c6b4">3</td>
            <td id="cell-a6a744c40c36">Tertiary eye center</td>
            <td id="cell-baa2c7e8e613">Fireworks injuries during celebrations</td>
            <td id="cell-947590e4bfb0">Civilian</td>
            <td id="cell-eefe0f993afd">Fireworks</td>
            <td id="cell-68a3c7ecc1ca">Severe open globe</td>
          </tr>
          <tr id="row-c912fe412933">
            <td id="cell-f498205ffbfb">Al Amry M et al., 2021†</td>
            <td id="cell-531eeb6d45fd">Saudi Arabia</td>
            <td id="cell-66bac864b412">Case series</td>
            <td id="cell-5d0ad5493361">36</td>
            <td id="cell-4cf0a5cd092b">Tertiary eye center, Riyadh</td>
            <td id="cell-5aaebd733454">Consecutive terror-related trauma</td>
            <td id="cell-d826cc735bca">Civilian</td>
            <td id="cell-51dd6c6206b8">Terror-related (blast)</td>
            <td id="cell-fae07c7e0ff3">77.8% NLP; devastating outcomes</td>
          </tr>
          <tr id="row-6d70e9a0ef81">
            <td id="cell-1c8e73d83494">Harris JP et al., 2021†</td>
            <td id="cell-00491176008c">Iraq</td>
            <td id="cell-54c7b4683306">Cohort</td>
            <td id="cell-8ea37e812d30">890 eyes</td>
            <td id="cell-0ee3c82f58f7">U.S. military registry</td>
            <td id="cell-a4639423907d">All combat open globe injuries</td>
            <td id="cell-371e1797b914">Military personnel</td>
            <td id="cell-c6e3212c7546">Blast</td>
            <td id="cell-889aca15ecbb">32.02% open globe injuries</td>
          </tr>
          <tr id="row-e7ebc09842ee">
            <td id="cell-524f7be8123a">Shakarchi F., 2025</td>
            <td id="cell-fea531a9066e">Iraq</td>
            <td id="cell-88ccf49ad10b">Cross-sectional (service)</td>
            <td id="cell-4d1cdcddb0b3">2805 primary health centers</td>
            <td id="cell-598fccdad3de">National primary care survey</td>
            <td id="cell-71fff0a37f11">All PHCs in Iraq</td>
            <td id="cell-4db5f2d26d8c">Civilian</td>
            <td id="cell-a10ddfa80ffb">Mixed (context)</td>
            <td id="cell-b806ce0eed0e">Only 2%(n=63) offer eye services</td>
          </tr>
          <tr id="row-5e4c9e5f1aa5">
            <td id="cell-a9a191f1ba44">Bahremani E et al., 2023</td>
            <td id="cell-a5b4c688b668">MENA region</td>
            <td id="cell-c40861c2a3fb">Cross-sectional (burden study)</td>
            <td id="cell-694af3c38669">Not specified</td>
            <td id="cell-1978636f9f29">Global Burden of Disease</td>
            <td id="cell-992810014da2">MENA population</td>
            <td id="cell-4dcd90e7332c">Civilian</td>
            <td id="cell-7ddf46a9c866">Mixed (all cause)</td>
            <td id="cell-a576223944a1">Iraq age-standardized prevalence 7188.6/100,000</td>
          </tr>
          <tr id="row-19d21e996b39">
            <td id="cell-97999463450c">Holmes CJ et al., 2019†</td>
            <td id="cell-b6a64de03a29">Iraq</td>
            <td id="cell-895fdca4006e">Cohort</td>
            <td id="cell-2ab733ba1785">19</td>
            <td id="cell-3ecbb342ad17">British military registry</td>
            <td id="cell-5f746bef0990">All combat eye injuries requiring surgery</td>
            <td id="cell-2780de285a18">Military personnel</td>
            <td id="cell-2e178dac930e">Blast/ fragmentation</td>
            <td id="cell-bf72dc7e8b68">Outcomes of evisceration/ enucleation</td>
          </tr>
          <tr id="row-e0ccecf5f250">
            <td id="cell-fa624b10c306">Keenan TDL et al., 2011†</td>
            <td id="cell-08a28f2924b5">Palestinian territories</td>
            <td id="cell-14d1f0bb2734">Case series</td>
            <td id="cell-e82be23068c5">32</td>
            <td id="cell-da7760941f52">Tertiary hospital, Gaza</td>
            <td id="cell-0bf9debd0fa7">Consecutive enucleations/ eviscerations</td>
            <td id="cell-2ee1923e5afb">Civilian/ mixed</td>
            <td id="cell-804074eae5c2">Conflict related</td>
            <td id="cell-79ca1cbbd60e">High rates of enucleation</td>
          </tr>
          <tr id="row-3948a0e6a7f1">
            <td id="cell-d45938b99e46">Ciftci MD et al., 2023</td>
            <td id="cell-dce88910f5cc">Turkey</td>
            <td id="cell-83691eb510a5">Case series (surgical technique)</td>
            <td id="cell-eaf8fefe6835">9</td>
            <td id="cell-82c85eb5a843">Tertiary eye center</td>
            <td id="cell-ae6012464ffb">Corneal perforations</td>
            <td id="cell-f2d5ab38ce5c">Civilian</td>
            <td id="cell-e8b58dae982f">Corneal perforations</td>
            <td id="cell-ea88c32f1f32">Sandwich technique + amniotic membrane is effective</td>
          </tr>
          <tr id="row-9bf5aa310937">
            <td id="cell-06e557a2f512">Arevalo JF et al., 2012</td>
            <td id="cell-0c7047b35e67">Saudi Arabia</td>
            <td id="cell-93630ddd7366">Review (Tier 2)</td>
            <td id="cell-23565adf078a">Not applicable</td>
            <td id="cell-1e8425693503">Not applicable</td>
            <td id="cell-5ae0d62f17e1">Not applicable</td>
            <td id="cell-d03b0ca4d002">Civilian</td>
            <td id="cell-0c30d54b7782">Penetrating trauma</td>
            <td id="cell-75e0daf9f000">Sympathetic ophthalmia prevention</td>
          </tr>
          <tr id="row-fbe2b5aa8f21">
            <td id="cell-084a3e415db7">Hayder Abdul Al Husain et al., 2023†</td>
            <td id="cell-e31360fe698e">Iraq</td>
            <td id="cell-913e8b4b425b">Cross sectional</td>
            <td id="cell-927e56968e97">120 pediatric patients</td>
            <td id="cell-0bab84e725cb">Pediatric ophthalmology clinic</td>
            <td id="cell-58e906eb0925">Consecutive clinic attendees</td>
            <td id="cell-f628cbb8c86f">Pediatric</td>
            <td id="cell-8dcbca54866d">Mixed</td>
            <td id="cell-a961981328f2">Home-occurring open globe wounds are preventable</td>
          </tr>
          <tr id="row-b13570326fdb">
            <td id="cell-25cc59ef01f7">Hosseini H et al., 2011†</td>
            <td id="cell-3138cb84633a">Iran</td>
            <td id="cell-999f901b2c00">Cross sectional</td>
            <td id="cell-253078a99e2a">278</td>
            <td id="cell-5e2e842cfad0">Tertiary hospital (southern Iran)</td>
            <td id="cell-ab8988302717">All pediatric ocular trauma</td>
            <td id="cell-e82a97f58da8">Pediatric</td>
            <td id="cell-3c232d2ed804">Sharp/blunt</td>
            <td id="cell-51b2ebc3287e">Boys predominantly affected</td>
          </tr>
        </tbody>
      </table>
      <table-wrap-foot>
        <p>MENA, Middle East and North Africa; NLP, No Light Perception; PHC, Primary Health Center; RTA, Road Traffic Accident. † Denotes studies included in the primary ocular trauma analysis.</p>
      </table-wrap-foot>
    </table-wrap>
    <table-wrap id="tbl-2" specific-use="aside-float: layout=full-width; anchor=blk-ba411164391d" position="float">
      <label>Table 2</label>
      <caption>
        <p>Comparison of Ocular Trauma Epidemiology Across Countries/Regions in the MENA Region (n = 25) Tier 1 (primary epidemiologic) studies are marked with †.</p>
      </caption>
      <table>
        <thead>
          <tr id="row-7270d8cc5b2e">
            <th id="cell-88d871a1846e">
              <bold>Author(s), Year</bold>
            </th>
            <th id="cell-c4a49cd16063">
              <bold>Country/ Region</bold>
            </th>
            <th id="cell-07ee9bda2084">
              <bold>Study Design</bold>
            </th>
            <th id="cell-e89e4b3f285c">
              <bold>Sample Size (N)</bold>
            </th>
            <th id="cell-29d8dc0abda0">
              <bold>Study Setting</bold>
            </th>
            <th id="cell-f9549f7aec48">
              <bold>Denominator / Population at Risk</bold>
            </th>
            <th id="cell-b5fcd72adc5f">
              <bold>Population</bold>
            </th>
            <th id="cell-92f2919adbbf">
              <bold>Primary Mechanism(s)</bold>
            </th>
            <th id="cell-857a4818f22e">
              <bold>Key Findings</bold>
            </th>
          </tr>
        </thead>
        <tbody>
          <tr id="row-1d0fbedbc1c8">
            <td id="cell-87e89a5ca637">Al Dahan D et al., 2019†</td>
            <td id="cell-59fb7374f579">Saudi Arabia</td>
            <td id="cell-c0843b21a925">Cross sectional</td>
            <td id="cell-bcdaf2bb3bba">199 pediatric prosthesis patients</td>
            <td id="cell-2d0cf448ff55">Tertiary referral center</td>
            <td id="cell-b83b1a98abd8">All pediatric prosthesis fittings</td>
            <td id="cell-e220a411cb12">Pediatric</td>
            <td id="cell-df2c65331709">Mixed</td>
            <td id="cell-5f2b430bf108">Prosthesis indications after trauma</td>
          </tr>
          <tr id="row-3a64a334e29f">
            <td id="cell-6bc3c4560f82">Masrur A et al., 2025†</td>
            <td id="cell-447cb2abe55b">Gaza (Palestine)</td>
            <td id="cell-0a7d57762316">Observational cohort</td>
            <td id="cell-b47d80bf4ecc">23</td>
            <td id="cell-ed883098807b">4 hospitals in Gaza</td>
            <td id="cell-76c984643a5b">Consecutive CNN registry cases (March–Sept 2024)</td>
            <td id="cell-338244862bd1">Pediatric (&lt;20 years)</td>
            <td id="cell-dbe5a1fd3ed3">Explosive / penetrating (conflict-related)</td>
            <td id="cell-ce8d53bc18b7">11/23 (48%) ocular trauma; severe visual loss including NLP; communication barriers main challenge</td>
          </tr>
          <tr id="row-4b7503152ea3">
            <td id="cell-d2fbb83bbb18">Mousavi B et al., 2009</td>
            <td id="cell-ae50a394fd47">Iran</td>
            <td id="cell-f50a0a18f773">Cross-sectional (chemical warfare)</td>
            <td id="cell-415fb8dedcd7">147</td>
            <td id="cell-5e1f737f4624">Chemical warfare survivor’s registry</td>
            <td id="cell-cfab2c0240af">Iranian chemical warfare survivors</td>
            <td id="cell-a7642271adfc">Civilian</td>
            <td id="cell-3f40832743a0">Chemical weapons</td>
            <td id="cell-45d1f1b98e72">Reduced quality of life</td>
          </tr>
          <tr id="row-a2cacb402e74">
            <td id="cell-feb7fd3766d2">Geiling J et al., 2012</td>
            <td id="cell-3fd9c8903878">Iraq</td>
            <td id="cell-8274f68912f7">Review (Tier 2)</td>
            <td id="cell-0318fbfd8c18">Not applicable</td>
            <td id="cell-93afdecfad3f">Not applicable</td>
            <td id="cell-aa9c42d18574">Not applicable</td>
            <td id="cell-08a340ade666">Military veterans</td>
            <td id="cell-d3524274d328">Conflict-related</td>
            <td id="cell-cff6c56679ec">Long-term care costs</td>
          </tr>
          <tr id="row-b959e7a288f5">
            <td id="cell-e692915959ea">Ramadhan HA et al., 2025†</td>
            <td id="cell-6cccb70f23ba">Iraq</td>
            <td id="cell-bc8461f99f31">Cross-sectional</td>
            <td id="cell-31be72549bc0">71</td>
            <td id="cell-61fbd0f9540c">Halabja population survey</td>
            <td id="cell-dc1e01da3e90">Chemically-exposed population</td>
            <td id="cell-6deb2b93d068">Civilian</td>
            <td id="cell-094202e88596">Chemical weapons</td>
            <td id="cell-286efc3dbfb5">Corneal injuries</td>
          </tr>
        </tbody>
      </table>
      <table-wrap-foot>
        <p>MENA, Middle East and North Africa; NLP, No Light Perception; PHC, Primary Health Center; RTA, Road Traffic Accident. † Denotes studies included in the primary ocular trauma analysis.</p>
      </table-wrap-foot>
    </table-wrap>
  </floats-group>
</article>
